Correlation of HER-2/neu Status with Estrogen (ER) & Progesterone (PR) Receptor in Breast Malignancies
نویسندگان
چکیده
منابع مشابه
Correlation of ER, PR, HER- 2 and P53 Immunoreactions with Clinico-Pathological Features in Breast Cancer
Background and Objectives: The most prevalent malignancy among women is known to be breast cancer (BC). Several factors contribute to determining tumor prognosis and treatment strategies. In this study, the frequency and relevance of these factors are discussed. Materials and Methods: This cross-sectional study was carried out on 214 patients with BC, who referred to the Cancer Institute of...
متن کاملRelation between Estrogen and Progesterone Receptor Status with p53, Ki67 and Her-2 Markers in Patients with Breast Cancer
Background: Breast cancer is the most common cancer in women, containing approximately one third of all illnesses in women. Assessment of molecular markers is valuable in predicting the outcome of disease and decision making for optimal treatment. The purpose of this study was to determine the relationship between estrogen and progesterone receptors with Her-2, Ki67, P53, and clinicopathologica...
متن کاملCorrelation of ER, PR and HER-2/Neu with other Prognostic Factors in Infiltrating Ductal Carcinoma of Breast
Background and Objectives: Breast cancer is the most common malignancy among women in the world. The aim of this study was to assess estrogen receptor (ER), progesterone receptor (PR) and HER-2/neu of infiltrating ductal carcinoma (IDC) with tumor size, histologic grade, lymph node metastasis and age. Methods: This study was carried out on 300 tissue blocks ofpatients with ID...
متن کاملExpression of Estrogen Receptor (ER) cx Protein in ER -positive Breast Cancer: Specific Correlation with Progesterone Receptor
Estrogen receptor (ER) cx, a splice variant of ER , is a dominant repressor of ER function. In this study we investigated the possibility that because the progesterone receptor (PR) gene is a downstream target of activated ER , in ER -positive breast cancers, expression of ER cx would result in repression of PR. In ER -positive MCF-7 cells, stable transfection of an ER cx expression vector resu...
متن کاملcorrelation of er, pr, her- 2 and p53 immunoreactions with clinico-pathological features in breast cancer
background and objectives: the most prevalent malignancy among women is known to be breast cancer (bc). several factors contribute to determining tumor prognosis and treatment strategies. in this study, the frequency and relevance of these factors are discussed. materials and methods: this cross-sectional study was carried out on 214 patients with bc, who referred to the cancer institute of im...
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ژورنال
عنوان ژورنال: Volume 34 Issue (1)
سال: 2020
ISSN: 2518-203X,1815-4905
DOI: 10.47489/p000s341z7391-9mc